PD‐L1 overexpression correlates with JAK2‐V617F mutational burden and is associated with 9p uniparental disomy in myeloproliferative neoplasms

Myeloproliferative neoplasms (MPN) are chronic stem cell disorders characterized by enhanced proliferation of myeloid cells, immune deregulation, and drug resistance. JAK2 somatic mutations drive the disease in 50–60% and CALR mutations in 25–30% of cases. Published data suggest that JAK2‐V617F‐muta...

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Detalles Bibliográficos
Autores principales: Milosevic Feenstra, Jelena D., Jäger, Roland, Schischlik, Fiorella, Ivanov, Daniel, Eisenwort, Gregor, Rumi, Elisa, Schuster, Michael, Gisslinger, Bettina, Machherndl‐Spandl, Sigrid, Bettelheim, Peter, Krauth, Maria‐Theresa, Keil, Felix, Bock, Christoph, Cazzola, Mario, Gisslinger, Heinz, Kralovics, Robert, Valent, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306481/
https://www.ncbi.nlm.nih.gov/pubmed/35015307
http://dx.doi.org/10.1002/ajh.26461

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