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Acetylcysteine has No Mechanistic Effect in Patients at Risk of Contrast‐Induced Nephropathy: A Failure of Academic Clinical Science

Contrast‐induced nephropathy (CIN) is a major complication of imaging in patients with chronic kidney disease (CKD). The publication of an academic randomized controlled trial (RCT; n = 83) reporting oral (N)‐acetylcysteine (NAC) to reduce CIN led to > 70 clinical trials, 23 systematic reviews, a...

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Detalles Bibliográficos
Autores principales: Sandilands, Euan A., Rees, Jessica M. B., Raja, Khuram, Dhaun, Neeraj, Morrison, Emma E., Hickson, Kirsty, Wraight, Jonathan, Gray, Tanya, Briody, Lesley, Cameron, Sharon, Thompson, Adrian P., Johnston, Neil R., Uren, Neal, Goddard, Jane, Treweeke, Andy, Rushworth, Gordon, Webb, David J., Bateman, D. Nicholas, Norrie, John, Megson, Ian L., Eddleston, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306485/
https://www.ncbi.nlm.nih.gov/pubmed/35098531
http://dx.doi.org/10.1002/cpt.2541