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Person‐centred care and short oral treatment for rifampicin‐resistant tuberculosis improve retention in care in Kandahar, Afghanistan

OBJECTIVES: To describe the effect of adaptations to a person‐centred care with short oral regimens on retention in care for rifampicin‐resistant TB (RR‐TB) in Kandahar province, Afghanistan. METHODS: The study included people with RR‐TB registered in the programme between 01 October 2016 and 18 Apr...

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Autores principales: Mesic, Anita, Ishaq, Sadiqullah, Khan, Waliullah H., Mureed, Atiqullah, Mar, Htay Thet, Khaing, Ei Ei, Bermudez‐Aza, Elkin, Rose, Letitia, Lynen, Lutgarde, Seddiq, Mohammad Khaled, Amirzada, Hashim Khan, Keus, Kees, Decroo, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306566/
https://www.ncbi.nlm.nih.gov/pubmed/34978748
http://dx.doi.org/10.1111/tmi.13716
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author Mesic, Anita
Ishaq, Sadiqullah
Khan, Waliullah H.
Mureed, Atiqullah
Mar, Htay Thet
Khaing, Ei Ei
Bermudez‐Aza, Elkin
Rose, Letitia
Lynen, Lutgarde
Seddiq, Mohammad Khaled
Amirzada, Hashim Khan
Keus, Kees
Decroo, Tom
author_facet Mesic, Anita
Ishaq, Sadiqullah
Khan, Waliullah H.
Mureed, Atiqullah
Mar, Htay Thet
Khaing, Ei Ei
Bermudez‐Aza, Elkin
Rose, Letitia
Lynen, Lutgarde
Seddiq, Mohammad Khaled
Amirzada, Hashim Khan
Keus, Kees
Decroo, Tom
author_sort Mesic, Anita
collection PubMed
description OBJECTIVES: To describe the effect of adaptations to a person‐centred care with short oral regimens on retention in care for rifampicin‐resistant TB (RR‐TB) in Kandahar province, Afghanistan. METHODS: The study included people with RR‐TB registered in the programme between 01 October 2016 and 18 April 2021. From 19 November 2019, the programme implemented a trial investigating the safety and effectiveness of short oral RR‐TB regimens. During the trial, person‐centred care was adapted. We included the data from people living with RR‐TB treated in the period before and after the care model was adapted and applied Kaplan‐Meier statistics to compare rates of retention in care. RESULTS: Of 236 patients registered in the RR‐TB programme, 146 (61.9%) were registered before and 90 (38.1%) after the model of care was adapted. Before adaptations enhancing person‐centred care, pre‐treatment attrition was 23.3% (n = 34/146), whilst under the adapted care model it was 5.6% (n = 5/90). Attrition on treatment was 22.3% (n = 25/112) before adaptations, whilst during the study period none of the participants were lost‐to‐follow‐up on treatment and 3.3% died (n = 3/90). CONCLUSIONS: As person‐centred care delivery and treatment regimens were adapted to better fit‐specific contextual challenges and the needs of the target population, retention in care improved amongst people with RR‐TB in Kandahar, Afghanistan.
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spelling pubmed-93065662022-07-28 Person‐centred care and short oral treatment for rifampicin‐resistant tuberculosis improve retention in care in Kandahar, Afghanistan Mesic, Anita Ishaq, Sadiqullah Khan, Waliullah H. Mureed, Atiqullah Mar, Htay Thet Khaing, Ei Ei Bermudez‐Aza, Elkin Rose, Letitia Lynen, Lutgarde Seddiq, Mohammad Khaled Amirzada, Hashim Khan Keus, Kees Decroo, Tom Trop Med Int Health Research Articles OBJECTIVES: To describe the effect of adaptations to a person‐centred care with short oral regimens on retention in care for rifampicin‐resistant TB (RR‐TB) in Kandahar province, Afghanistan. METHODS: The study included people with RR‐TB registered in the programme between 01 October 2016 and 18 April 2021. From 19 November 2019, the programme implemented a trial investigating the safety and effectiveness of short oral RR‐TB regimens. During the trial, person‐centred care was adapted. We included the data from people living with RR‐TB treated in the period before and after the care model was adapted and applied Kaplan‐Meier statistics to compare rates of retention in care. RESULTS: Of 236 patients registered in the RR‐TB programme, 146 (61.9%) were registered before and 90 (38.1%) after the model of care was adapted. Before adaptations enhancing person‐centred care, pre‐treatment attrition was 23.3% (n = 34/146), whilst under the adapted care model it was 5.6% (n = 5/90). Attrition on treatment was 22.3% (n = 25/112) before adaptations, whilst during the study period none of the participants were lost‐to‐follow‐up on treatment and 3.3% died (n = 3/90). CONCLUSIONS: As person‐centred care delivery and treatment regimens were adapted to better fit‐specific contextual challenges and the needs of the target population, retention in care improved amongst people with RR‐TB in Kandahar, Afghanistan. John Wiley and Sons Inc. 2022-01-17 2022-02 /pmc/articles/PMC9306566/ /pubmed/34978748 http://dx.doi.org/10.1111/tmi.13716 Text en © 2022 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Mesic, Anita
Ishaq, Sadiqullah
Khan, Waliullah H.
Mureed, Atiqullah
Mar, Htay Thet
Khaing, Ei Ei
Bermudez‐Aza, Elkin
Rose, Letitia
Lynen, Lutgarde
Seddiq, Mohammad Khaled
Amirzada, Hashim Khan
Keus, Kees
Decroo, Tom
Person‐centred care and short oral treatment for rifampicin‐resistant tuberculosis improve retention in care in Kandahar, Afghanistan
title Person‐centred care and short oral treatment for rifampicin‐resistant tuberculosis improve retention in care in Kandahar, Afghanistan
title_full Person‐centred care and short oral treatment for rifampicin‐resistant tuberculosis improve retention in care in Kandahar, Afghanistan
title_fullStr Person‐centred care and short oral treatment for rifampicin‐resistant tuberculosis improve retention in care in Kandahar, Afghanistan
title_full_unstemmed Person‐centred care and short oral treatment for rifampicin‐resistant tuberculosis improve retention in care in Kandahar, Afghanistan
title_short Person‐centred care and short oral treatment for rifampicin‐resistant tuberculosis improve retention in care in Kandahar, Afghanistan
title_sort person‐centred care and short oral treatment for rifampicin‐resistant tuberculosis improve retention in care in kandahar, afghanistan
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306566/
https://www.ncbi.nlm.nih.gov/pubmed/34978748
http://dx.doi.org/10.1111/tmi.13716
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