Pharmacological characterization of novel heteromeric GluCl subtypes from Caenorhabditis elegans and parasitic nematodes

BACKGROUND AND PURPOSE: Macrocyclic lactones are the most widely used broad‐spectrum anthelmintic drugs for the treatment of parasitic nematodes affecting both human and animal health. Macrocyclic lactones are agonists of the nematode glutamate‐gated chloride channels (GluCls). However, for many imp...

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Detalles Bibliográficos
Autores principales: Lamassiaude, Nicolas, Courtot, Elise, Corset, Angélique, Charvet, Claude L., Neveu, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306661/
https://www.ncbi.nlm.nih.gov/pubmed/34623639
http://dx.doi.org/10.1111/bph.15703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306661/
https://www.ncbi.nlm.nih.gov/pubmed/34623639
http://dx.doi.org/10.1111/bph.15703

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