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Pharmacological characterization of novel heteromeric GluCl subtypes from Caenorhabditis elegans and parasitic nematodes
BACKGROUND AND PURPOSE: Macrocyclic lactones are the most widely used broad‐spectrum anthelmintic drugs for the treatment of parasitic nematodes affecting both human and animal health. Macrocyclic lactones are agonists of the nematode glutamate‐gated chloride channels (GluCls). However, for many imp...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306661/ https://www.ncbi.nlm.nih.gov/pubmed/34623639 http://dx.doi.org/10.1111/bph.15703 |