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Reduced Numbers of Corticotropin‐Releasing Hormone Neurons in Narcolepsy Type 1

Narcolepsy type 1 (NT1) is a chronic sleep disorder correlated with loss of hypocretin(orexin). In NT1 post‐mortem brains, we observed 88% reduction in corticotropin‐releasing hormone (CRH)‐positive neurons in the paraventricular nucleus (PVN) and significantly less CRH‐positive fibers in the median...

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Detalles Bibliográficos
Autores principales: Shan, Ling, Balesar, Rawien, Swaab, Dick F., Lammers, Gert Jan, Fronczek, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306683/
https://www.ncbi.nlm.nih.gov/pubmed/34981555
http://dx.doi.org/10.1002/ana.26300