Cargando…
Substrate Profiling of Mitochondrial Caseinolytic Protease P via a Site‐Specific Photocrosslinking Approach
Approaches for profiling protease substrates are critical for defining protease functions, but remain challenging tasks. We combine genetic code expansion, photocrosslinking and proteomics to identify substrates of the mitochondrial (mt) human caseinolytic protease P (hClpP). Site‐specific incorpora...
Autores principales: | Nguyen, Tuan‐Anh, Gronauer, Thomas F., Nast‐Kolb, Timon, Sieber, Stephan A., Lang, Kathrin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306725/ https://www.ncbi.nlm.nih.gov/pubmed/34847623 http://dx.doi.org/10.1002/anie.202111085 |
Ejemplares similares
-
Mycobacterial Caseinolytic Protease Gene Regulator ClgR Is a Substrate of Caseinolytic Protease
por: Yamada, Yoshiyuki, et al.
Publicado: (2017) -
The structure of caseinolytic protease subunit ClpP2 reveals a functional model of the caseinolytic protease system from Chlamydia trachomatis
por: Azadmanesh, Jahaun, et al.
Publicado: (2022) -
Acyldepsipeptide Probes Facilitate Specific Detection of Caseinolytic Protease P Independent of Its Oligomeric and Activity State
por: Eyermann, Barbara, et al.
Publicado: (2020) -
Mitochondrial Caseinolytic Protease P: A Possible Novel Prognostic Marker and Therapeutic Target in Cancer
por: Cormio, Antonella, et al.
Publicado: (2021) -
Reprogramming of the Caseinolytic Protease by ADEP Antibiotics: Molecular Mechanism, Cellular Consequences, Therapeutic Potential
por: Brötz-Oesterhelt, Heike, et al.
Publicado: (2021)