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Indomethacin Polymorph δ Revealed To Be Two Plastically Bendable Crystal Forms by 3D Electron Diffraction: Correcting a 47‐Year‐Old Misunderstanding
Indomethacin is a clinically classical non‐steroidal anti‐inflammatory drug that has been marketed since 1965. The third polymorph, Form δ, was discovered by both melt and solution crystallization in 1974. δ‐indomethacin cannot be cultivated as large single crystals suitable for X‐ray crystallograph...
Autores principales: | Lightowler, Molly, Li, Shuting, Ou, Xiao, Zou, Xiaodong, Lu, Ming, Xu, Hongyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306882/ https://www.ncbi.nlm.nih.gov/pubmed/34902212 http://dx.doi.org/10.1002/anie.202114985 |
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