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Dissociative symptomatology mediates the relation between posttraumatic stress disorder severity and alcohol‐related problems

BACKGROUND: Up to 50% of individuals with posttraumatic stress disorder (PTSD) endorse problematic alcohol use. Typically, these individuals present with more complex and often more severe PTSD symptoms than those who do not report problematic alcohol use. Emerging literature suggests that heightene...

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Autores principales: Patel, Herry, O’Connor, Charlene, Andrews, Krysta, Amlung, Michael, Lanius, Ruth, McKinnon, Margaret C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307004/
https://www.ncbi.nlm.nih.gov/pubmed/35179786
http://dx.doi.org/10.1111/acer.14764
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author Patel, Herry
O’Connor, Charlene
Andrews, Krysta
Amlung, Michael
Lanius, Ruth
McKinnon, Margaret C.
author_facet Patel, Herry
O’Connor, Charlene
Andrews, Krysta
Amlung, Michael
Lanius, Ruth
McKinnon, Margaret C.
author_sort Patel, Herry
collection PubMed
description BACKGROUND: Up to 50% of individuals with posttraumatic stress disorder (PTSD) endorse problematic alcohol use. Typically, these individuals present with more complex and often more severe PTSD symptoms than those who do not report problematic alcohol use. Emerging literature suggests that heightened symptoms of dissociation are likewise associated with greater PTSD symptom severity. Despite this knowledge, the role of dissociation in the relation between PTSD severity and alcohol‐related problems has yet to be examined. Here, we explore the mediating role of dissociative symptomatology on the association between PTSD severity and alcohol‐related problems within a PTSD treatment‐seeking sample. METHODS: Structural equation modeling was used to test the mediating role of dissociative symptomatology between PTSD severity and alcohol‐related problems. Participants [N = 334; mean age (SD) = 44.29 (9.77), 50% female] were drawn from a clinical intake battery database for PTSD in‐patient treatment services at Homewood Health Care, Guelph, ON, Canada. A subset of battery measures assessing PTSD severity, dissociative symptomatology, and alcohol‐related problems were submitted to analysis. RESULTS: A significant positive association emerged between PTSD severity and alcohol‐related problems (β = 0.127, p < 0.05) in the absence of dissociative symptomatology. Critically, however, when added to this model, dissociative symptomatology (six unique facets of dissociation assessed by the Multiscale Dissociation Inventory) mediated the relation between PTSD severity and alcohol‐related problems. Specifically, greater PTSD severity was associated with greater dissociative symptomatology (β = 0.566, p < 0.0001), which was in turn associated with greater alcohol‐related problems (β = 0.184, p < 0.05). CONCLUSIONS: These results suggest that dissociative symptomatology plays a key role in explaining the relation between PTSD severity and alcohol‐related problems. Future studies should examine the impact of targeting dissociative symptomatology specifically in treating individuals with PTSD who endorse alcohol‐related problems.
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spelling pubmed-93070042022-07-28 Dissociative symptomatology mediates the relation between posttraumatic stress disorder severity and alcohol‐related problems Patel, Herry O’Connor, Charlene Andrews, Krysta Amlung, Michael Lanius, Ruth McKinnon, Margaret C. Alcohol Clin Exp Res Behavior, Treatment and Prevention BACKGROUND: Up to 50% of individuals with posttraumatic stress disorder (PTSD) endorse problematic alcohol use. Typically, these individuals present with more complex and often more severe PTSD symptoms than those who do not report problematic alcohol use. Emerging literature suggests that heightened symptoms of dissociation are likewise associated with greater PTSD symptom severity. Despite this knowledge, the role of dissociation in the relation between PTSD severity and alcohol‐related problems has yet to be examined. Here, we explore the mediating role of dissociative symptomatology on the association between PTSD severity and alcohol‐related problems within a PTSD treatment‐seeking sample. METHODS: Structural equation modeling was used to test the mediating role of dissociative symptomatology between PTSD severity and alcohol‐related problems. Participants [N = 334; mean age (SD) = 44.29 (9.77), 50% female] were drawn from a clinical intake battery database for PTSD in‐patient treatment services at Homewood Health Care, Guelph, ON, Canada. A subset of battery measures assessing PTSD severity, dissociative symptomatology, and alcohol‐related problems were submitted to analysis. RESULTS: A significant positive association emerged between PTSD severity and alcohol‐related problems (β = 0.127, p < 0.05) in the absence of dissociative symptomatology. Critically, however, when added to this model, dissociative symptomatology (six unique facets of dissociation assessed by the Multiscale Dissociation Inventory) mediated the relation between PTSD severity and alcohol‐related problems. Specifically, greater PTSD severity was associated with greater dissociative symptomatology (β = 0.566, p < 0.0001), which was in turn associated with greater alcohol‐related problems (β = 0.184, p < 0.05). CONCLUSIONS: These results suggest that dissociative symptomatology plays a key role in explaining the relation between PTSD severity and alcohol‐related problems. Future studies should examine the impact of targeting dissociative symptomatology specifically in treating individuals with PTSD who endorse alcohol‐related problems. John Wiley and Sons Inc. 2022-02-18 2022-02 /pmc/articles/PMC9307004/ /pubmed/35179786 http://dx.doi.org/10.1111/acer.14764 Text en © 2022 The Authors. Alcoholism: Clinical & Experimental Research published by Wiley Periodicals LLC on behalf of Research Society on Alcoholism. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Behavior, Treatment and Prevention
Patel, Herry
O’Connor, Charlene
Andrews, Krysta
Amlung, Michael
Lanius, Ruth
McKinnon, Margaret C.
Dissociative symptomatology mediates the relation between posttraumatic stress disorder severity and alcohol‐related problems
title Dissociative symptomatology mediates the relation between posttraumatic stress disorder severity and alcohol‐related problems
title_full Dissociative symptomatology mediates the relation between posttraumatic stress disorder severity and alcohol‐related problems
title_fullStr Dissociative symptomatology mediates the relation between posttraumatic stress disorder severity and alcohol‐related problems
title_full_unstemmed Dissociative symptomatology mediates the relation between posttraumatic stress disorder severity and alcohol‐related problems
title_short Dissociative symptomatology mediates the relation between posttraumatic stress disorder severity and alcohol‐related problems
title_sort dissociative symptomatology mediates the relation between posttraumatic stress disorder severity and alcohol‐related problems
topic Behavior, Treatment and Prevention
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307004/
https://www.ncbi.nlm.nih.gov/pubmed/35179786
http://dx.doi.org/10.1111/acer.14764
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