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14-3-3-zeta mediates GLP-1 receptor agonist action to alter α cell proglucagon processing

Recent studies demonstrate that α cells contribute to glucose-stimulated insulin secretion (GSIS). Glucagon-like peptide-1 receptor (GLP-1R) agonists potently potentiate GSIS, making these drugs useful for diabetes treatment. However, the role of α and β cell paracrine interactions in the effects of...

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Detalles Bibliográficos
Autores principales:	Holter, Marlena M., Phuong, Daryl J., Lee, Isaac, Saikia, Mridusmita, Weikert, Lisa, Fountain, Samantha, Anderson, Elizabeth T., Fu, Qin, Zhang, Sheng, Sloop, Kyle W., Cummings, Bethany P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307243/ https://www.ncbi.nlm.nih.gov/pubmed/35867787 http://dx.doi.org/10.1126/sciadv.abn3773

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