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Hypoxia-mediated stabilization of HIF1A in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression

Prostate cancer (PCa) is a leading cause of cancer-related deaths. The slow evolution of precancerous lesions to malignant tumors provides a broad time frame for preventing PCa. To characterize prostatic intraepithelial neoplasia (PIN) progression, we conducted longitudinal studies on Pten((i)pe−/−)...

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Detalles Bibliográficos
Autores principales:	Abu el Maaty, Mohamed A., Terzic, Julie, Keime, Céline, Rovito, Daniela, Lutzing, Régis, Yanushko, Darya, Parisotto, Maxime, Grelet, Elise, Namer, Izzie Jacques, Lindner, Véronique, Laverny, Gilles, Metzger, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307253/ https://www.ncbi.nlm.nih.gov/pubmed/35867798 http://dx.doi.org/10.1126/sciadv.abo2295

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