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Choroidal endothelial and macrophage gene expression in atrophic and neovascular macular degeneration

The human choroid is a heterogeneous, highly vascular connective tissue that dysfunctions in age-related macular degeneration (AMD). In this study, we performed single-cell RNA sequencing on 21 human choroids, 11 of which were derived from donors with early atrophic or neovascular AMD. Using this la...

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Detalles Bibliográficos
Autores principales: Voigt, Andrew P, Mullin, Nathaniel K, Mulfaul, Kelly, Lozano, Lola P, Wiley, Luke A, Flamme-Wiese, Miles J, Boese, Erin A, Han, Ian C, Scheetz, Todd E, Stone, Edwin M, Tucker, Budd A, Mullins, Robert F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307320/
https://www.ncbi.nlm.nih.gov/pubmed/35181781
http://dx.doi.org/10.1093/hmg/ddac043