Cargando…

Icariin Regulates the hsa_circ_0003159/eIF4A3/bcl-2 Axis to Promote Gastric Cancer Cell Apoptosis

OBJECTIVE: To clarify the mechanism of icariin (ICA) promoting gastric cancer (GC) cell apoptosis by regulating circ_0003159/eIF4A3/bcl-2 axis. METHODS: The mRNA or protein levels were detected by qRT-PCR or the western blot. The interaction between eIF4A3 protein and circ_0003159 or eIF4A3 protein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Yanfen, Xu, Wenwen, Song, Yanan, Zhou, Zhou, Sun, Xin, Zhang, Fengli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307325/ https://www.ncbi.nlm.nih.gov/pubmed/35873631 http://dx.doi.org/10.1155/2022/1955101

Ejemplares similares

Hsa_circ_0003159 inhibits gastric cancer progression by regulating miR-223-3p/NDRG1 axis
por: Wang, Jingyu, et al.
Publicado: (2020)

Clinical significances of hsa_circ_0067582 and hsa_circ_0005758 in gastric cancer tissues
por: Lu, Rongdan, et al.
Publicado: (2019)

hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP
por: Liang, Jian, et al.
Publicado: (2021)

hsa_circ_0006459 and hsa_circ_0015962 affect prognosis of Dengue fever
por: He, JinHua, et al.
Publicado: (2019)

Serum and Serum Exosomal CircRNAs hsa_circ_0001492, hsa_circ_0001439, and hsa_circ_0000896 as Diagnostic Biomarkers for Lung Adenocarcinoma
por: Kang, Yanli, et al.
Publicado: (2022)

Potential roles of hsa_circ_000839 and hsa_circ_0005986 in breast cancer
por: Firoozi, Zahra, et al.
Publicado: (2022)

Hsa_circ_0028502 and hsa_circ_0076251 are potential novel biomarkers for hepatocellular carcinoma
por: Jiang, Zhenluo, et al.
Publicado: (2019)

Hsa_circ_0053063 inhibits breast cancer cell proliferation via hsa_circ_0053063/hsa-miR-330-3p/PDCD4 axis
por: Ji, Changle, et al.
Publicado: (2021)

Bioinformatics Analysis: The Regulatory Network of hsa_circ_0007843 and hsa_circ_0007331 in Colon Cancer
por: Han, Zeping, et al.
Publicado: (2021)

A novel circRNA, hsa_circ_0069382, regulates gastric cancer progression
por: Wang, Haoying, et al.
Publicado: (2023)

Plasma Circular RNAs hsa_circ_0001953 and hsa_circ_0009024 as Diagnostic Biomarkers for Active Tuberculosis
por: Huang, Zikun, et al.
Publicado: (2018)

Hsa_circ_0000497 and hsa_circ_0000918 contributed to peritoneal metastasis of ovarian cancer via ascites
por: Luo, Ning, et al.
Publicado: (2022)

Exosomal circular RNA hsa_circ_0006220, and hsa_circ_0001666 as biomarkers in the diagnosis of pancreatic cancer
por: Hong, Lu, et al.
Publicado: (2022)

Tumor suppressor role of hsa_circ_0035445 in gastric cancer
por: Sun, Weiliang, et al.
Publicado: (2021)

Circular RNA hsa_circ_0001874 is an indicator for gastric cancer
por: Ye, Qihua, et al.
Publicado: (2021)

Circular RNAs hsa_circ_0032462, hsa_circ_0028173, hsa_circ_0005909 are predicted to promote CADM1 expression by functioning as miRNAs sponge in human osteosarcoma
por: Chen, Gaoyang, et al.
Publicado: (2018)

Identification of circular RNAs hsa_circ_0044235 and hsa_circ_0068367 as novel biomarkers for systemic lupus erythematosus
por: Luo, Qing, et al.
Publicado: (2019)

Circular RNAs Hsa_circ_101555 and Hsa_circ_008068 as Diagnostic Biomarkers for Early-Stage Lung Adenocarcinoma
por: Lian, Xue, et al.
Publicado: (2022)

Expression Profiles of circRNAs and Identification of hsa_circ_0007608 and hsa_circ_0064656 as Potential Biomarkers for COPD-PH Patients
por: Yu, Jinyan, et al.
Publicado: (2023)

Downregulated Expression of hsa_circ_0005556 in Gastric Cancer and Its Clinical Significance
por: Yang, Liangwei, et al.
Publicado: (2019)

Decreased Expression of Hsa_circ_00001649 in Gastric Cancer and Its Clinical Significance
por: Li, Wen-han, et al.
Publicado: (2017)

Hsa_circ_0012152 and Hsa_circ_0001857 Accurately Discriminate Acute Lymphoblastic Leukemia From Acute Myeloid Leukemia
por: Guo, Shanshan, et al.
Publicado: (2020)

Hsa_circ_0076305 induces migration-proliferation dichotomy in gastric cancer
por: Zhang, Yuhai, et al.
Publicado: (2021)

Circular RNA hsa_circ_0006401 promotes proliferation and metastasis in colorectal carcinoma
por: Zhang, Chenjing, et al.
Publicado: (2021)

Circular RNA hsa_circ_0003288 induces EMT and invasion by regulating hsa_circ_0003288/miR-145/PD-L1 axis in hepatocellular carcinoma
por: Xu, Guili, et al.
Publicado: (2021)

Circular RNA hsa_circ_0005046 and hsa_circ_0001791 May Become Diagnostic Biomarkers for Breast Cancer Early Detection
por: Ameli-Mojarad, Melika, et al.
Publicado: (2021)

The hsa_circ_0007396-miR-767-3p-CHD4 axis is involved in the progression and carcinogenesis of gastric cancer
por: Wang, Yantao, et al.
Publicado: (2022)

Reduced expression of circRNA hsa_circ_0067582 in human gastric cancer and its potential diagnostic values
por: Yu, Xiuchong, et al.
Publicado: (2019)

Reduced expression of circRNA hsa_circ_001888 in gastric cancer and its clinical significance
por: Shi, Peina, et al.
Publicado: (2021)

Upregulation of hsa_circ_0002003 promotes hepatocellular carcinoma progression
por: Zhou, Lisha, et al.
Publicado: (2023)

Roles of the hsa_circ_0013880/USP32/Rap1b axis in the proliferation and apoptosis of acute myeloid leukemia cells: hsa_circ_0013880/USP32/Rap1b in acute myeloid leukemia
por: Zhang, Heyang, et al.
Publicado: (2023)

Mapping CircRNA–miRNA–mRNA regulatory axis identifies hsa_circ_0080942 and hsa_circ_0080135 as a potential theranostic agents for SARS-CoV-2 infection
por: Ayaz, Hassan, et al.
Publicado: (2023)

Downregulated hsa_circ_0077837 and hsa_circ_0004826, facilitate bladder cancer progression and predict poor prognosis for bladder cancer patients
por: Shen, Chong, et al.
Publicado: (2020)

Circular RNAs Hsa_circ_0002715 and Hsa_circ_0035197 in Peripheral Blood Are Novel Potential Biomarkers for New-Onset Rheumatoid Arthritis
por: Luo, Qing, et al.
Publicado: (2019)

Diagnostic significance of hsa_circ_0000146 and hsa_circ_0000072 biomarkers for Diabetic Kidney Disease in patients with type 2 diabetes mellitus
por: Badr, Amul M., et al.
Publicado: (2023)

Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma
por: Yuan, Fanen, et al.
Publicado: (2022)

Hsa_circ_0005729 enhances accuracy in diagnosing parathyroid carcinoma
por: Wang, Qian, et al.
Publicado: (2022)

Hsa_circ_0002348 regulates trophoblast proliferation and apoptosis through miR-126-3p/BAK1 axis in preeclampsia
por: Zhou, Jizi, et al.
Publicado: (2023)

Hsa_circ_0030042 regulates abnormal autophagy and protects atherosclerotic plaque stability by targeting eIF4A3
por: Yu, Fangpu, et al.
Publicado: (2021)

hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3
por: Wang, Xuehui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_on7rdc68tcjvq2b0qkgnhqoai0