Melatonin Attenuates Methotrexate-Induced Reduction of Antioxidant Activity Related to Decreases of Neurogenesis in Adult Rat Hippocampus and Prefrontal Cortex

Previous studies have revealed that the side effects of anticancer drugs induce a decrease of neurogenesis. Methotrexate (MTX), one of anticancer drugs, can induce lipid peroxidation as an indicator of oxidative stress in the brain. Melatonin has been presented as an antioxidant that can prevent oxi...

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Detalles Bibliográficos
Autores principales: Suwannakot, Kornrawee, Sritawan, Nataya, Naewla, Salinee, Aranarochana, Anusara, Sirichoat, Apiwat, Pannangrong, Wanassanun, Wigmore, Peter, Welbat, Jariya Umka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307408/
https://www.ncbi.nlm.nih.gov/pubmed/35873801
http://dx.doi.org/10.1155/2022/1596362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307408/
https://www.ncbi.nlm.nih.gov/pubmed/35873801
http://dx.doi.org/10.1155/2022/1596362

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