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Melatonin Attenuates Methotrexate-Induced Reduction of Antioxidant Activity Related to Decreases of Neurogenesis in Adult Rat Hippocampus and Prefrontal Cortex
Previous studies have revealed that the side effects of anticancer drugs induce a decrease of neurogenesis. Methotrexate (MTX), one of anticancer drugs, can induce lipid peroxidation as an indicator of oxidative stress in the brain. Melatonin has been presented as an antioxidant that can prevent oxi...
Autores principales: | Suwannakot, Kornrawee, Sritawan, Nataya, Naewla, Salinee, Aranarochana, Anusara, Sirichoat, Apiwat, Pannangrong, Wanassanun, Wigmore, Peter, Welbat, Jariya Umka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307408/ https://www.ncbi.nlm.nih.gov/pubmed/35873801 http://dx.doi.org/10.1155/2022/1596362 |
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