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Therapeutic effect of NLRP3 inhibition on hearing loss induced by systemic inflammation in a CAPS-associated mouse model

BACKGROUND: Cryopyrin-associated periodic syndrome (CAPS) is an inherited autoinflammatory disease caused by a gain-of-function mutation in NLRP3. Although CAPS patients frequently suffer from sensorineural hearing loss, it remains unclear whether CAPS-associated mutation in NLRP3 is associated with...

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Detalles Bibliográficos
Autores principales:	Ma, Ji-Hyun, Lee, Eunju, Yoon, Sung-Hyun, Min, Hyehyun, Oh, Jae Hwan, Hwang, Inhwa, Sung, Yejin, Ryu, Ju Hee, Bok, Jinwoong, Yu, Je-Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307460/ https://www.ncbi.nlm.nih.gov/pubmed/35870427 http://dx.doi.org/10.1016/j.ebiom.2022.104184

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