Genome-wide association study in minority children with asthma implicates DNAH5 in bronchodilator responsiveness

Variability in response to short-acting β(2)-agonists (e.g., albuterol) among patients with asthma from diverse racial/ethnic groups may contribute to asthma disparities. We sought to identify genetic variants associated with bronchodilator response (BDR) to identify potential mechanisms of drug res...

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Detalles Bibliográficos
Autores principales: Joo, Jaehyun, Mak, Angel C. Y., Xiao, Shujie, Sleiman, Patrick M., Hu, Donglei, Huntsman, Scott, Eng, Celeste, Kan, Mengyuan, Diwakar, Avantika R., Lasky-Su, Jessica A., Weiss, Scott T., Sordillo, Joanne E., Wu, Ann C., Cloutier, Michelle, Canino, Glorisa, Forno, Erick, Celedón, Juan C., Seibold, Max A., Hakonarson, Hakon, Williams, L. Keoki, Burchard, Esteban G., Himes, Blanca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307508/
https://www.ncbi.nlm.nih.gov/pubmed/35869121
http://dx.doi.org/10.1038/s41598-022-16488-6

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