Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases

Lung cancer is one of the most common cancers, and the number of patients with intracranial metastases is increasing. Previously, we developed an enzyme prodrug suicide gene therapy based on the herpes simplex virus thymidine kinase (HSV-TK)/ganciclovir (GCV) system using various mesenchymal stem ce...

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Detalles Bibliográficos
Autores principales: Oishi, Tomoya, Ito, Masahiko, Koizumi, Shinichiro, Horikawa, Makoto, Yamamoto, Taisuke, Yamagishi, Satoru, Yamasaki, Tomohiro, Sameshima, Tetsuro, Suzuki, Tetsuro, Sugimura, Haruhiko, Namba, Hiroki, Kurozumi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307584/
https://www.ncbi.nlm.nih.gov/pubmed/35892087
http://dx.doi.org/10.1016/j.omtm.2022.07.001

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