OMiCC: An expanded and enhanced platform for meta-analysis of public gene expression data

OMiCC (OMics Compendia Commons) is a biologist-friendly web platform that facilitates data reuse and integration. Users can search over 40,000 publicly available gene expression studies, annotate and curate samples, and perform meta-analysis. Since the initial publication, we have incorporated RNA-s...

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Detalles Bibliográficos
Autores principales: Liu, Candace C., Guo, Yongjian, Vrindten, Kiera L., Lau, William W., Sparks, Rachel, Tsang, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307621/
https://www.ncbi.nlm.nih.gov/pubmed/35880119
http://dx.doi.org/10.1016/j.xpro.2022.101474
Descripción
Sumario:OMiCC (OMics Compendia Commons) is a biologist-friendly web platform that facilitates data reuse and integration. Users can search over 40,000 publicly available gene expression studies, annotate and curate samples, and perform meta-analysis. Since the initial publication, we have incorporated RNA-seq datasets, compendia sharing, RESTful API support, and an additional meta-analysis method based on random effects. Here, we provide a step-by-step guide for using OMiCC. For complete details on the use and execution of this protocol, please refer to Shah et al. (2016).

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