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The molecular heterogeneity of the precancerous breast affects drug efficacy

In the therapeutic domain, targeted therapies have been shown to be generally more effective when given to patients with tumors that harbor the targeted aberration. This principle has not been tested in cancer prevention despite evidence that molecular heterogeneity accompanies the multi-step progre...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Anjana, Rojo, Raniv Dawey, Ju, Zhenlin, Koh, Alexander, Tachibana, Kazunoshin, Wang, Jing, Bedrosian, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307756/
https://www.ncbi.nlm.nih.gov/pubmed/35869155
http://dx.doi.org/10.1038/s41598-022-16779-y