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The molecular heterogeneity of the precancerous breast affects drug efficacy
In the therapeutic domain, targeted therapies have been shown to be generally more effective when given to patients with tumors that harbor the targeted aberration. This principle has not been tested in cancer prevention despite evidence that molecular heterogeneity accompanies the multi-step progre...
Autores principales: | Bhardwaj, Anjana, Rojo, Raniv Dawey, Ju, Zhenlin, Koh, Alexander, Tachibana, Kazunoshin, Wang, Jing, Bedrosian, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307756/ https://www.ncbi.nlm.nih.gov/pubmed/35869155 http://dx.doi.org/10.1038/s41598-022-16779-y |
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