Structure-based prediction of BRAF mutation classes using machine-learning approaches

The BRAF kinase is attracting a lot of attention in oncology as alterations of its amino acid sequence can constitutively activate the MAP kinase signaling pathway, potentially contributing to the malignant transformation of the cell but at the same time rendering it sensitive to targeted therapy. S...

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Detalles Bibliográficos
Autores principales: Krebs, Fanny S., Britschgi, Christian, Pradervand, Sylvain, Achermann, Rita, Tsantoulis, Petros, Haefliger, Simon, Wicki, Andreas, Michielin, Olivier, Zoete, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307832/
https://www.ncbi.nlm.nih.gov/pubmed/35869122
http://dx.doi.org/10.1038/s41598-022-16556-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307832/
https://www.ncbi.nlm.nih.gov/pubmed/35869122
http://dx.doi.org/10.1038/s41598-022-16556-x

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