Calcium/calmodulin-dependent protein kinase IV promotes imiquimod-induced psoriatic inflammation via macrophages and keratinocytes in mice

CaMK4 has an important function in autoimmune diseases, and the contribution of CaMK4 in psoriasis remains obscure. Here, we show that CaMK4 expression is significantly increased in psoriatic lesional skin from psoriasis patients compared to healthy human skin as well as inflamed skin from an imiqui...

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Detalles Bibliográficos
Autores principales: Yong, Liang, Yu, Yafen, Li, Bao, Ge, Huiyao, Zhen, Qi, Mao, Yiwen, Yu, Yanxia, Cao, Lu, Zhang, Ruixue, Li, Zhuo, Wang, Yirui, Fan, Wencheng, Zhang, Chang, Wang, Daiyue, Luo, Sihan, Bai, Yuanming, Chen, Shirui, Chen, Weiwei, Liu, Miao, Shen, Jijia, Sun, Liangdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307837/
https://www.ncbi.nlm.nih.gov/pubmed/35869084
http://dx.doi.org/10.1038/s41467-022-31935-8

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