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Mitotic SENP3 activation couples with cGAS signaling in tumor cells to stimulate anti-tumor immunity

Our previous studies show that the mitotic phosphorylation of SUMO-specific protease 3 (SENP3) can inhibit its de-SUMOylation activity in G2/M phase of the cell cycle. Inhibition of SENP3 plays a critical role in the correct separation of sister chromatids in mitosis. The mutation of mitotic SENP3 p...

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Detalles Bibliográficos
Autores principales:	Hu, Gaolei, Chen, Yalan, Yang, Xinyu, Wang, Yang, He, Jianli, Wang, Tianshi, Fan, Qiuju, Deng, Liufu, Tu, Jun, Tan, Hongsheng, Cheng, Jinke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307842/ https://www.ncbi.nlm.nih.gov/pubmed/35869062 http://dx.doi.org/10.1038/s41419-022-05063-6

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