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ACSL4 is essential for radiation-induced intestinal injury by initiating ferroptosis

Lipid peroxidation-induced ferroptosis is a newly recognized type of programmed cell death. With the method of RNA sequencing, we found that irradiation (IR) markedly increased the expression of ferroptosis promotive genes, whereas reduced the expression of ferroptosis suppressive genes in murine in...

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Detalles Bibliográficos
Autores principales: Ji, Qian, Fu, Shengqiao, Zuo, Hao, Huang, Yumeng, Chu, Liangmei, Zhu, Yanyan, Hu, Jing, Wu, Yuting, Chen, Shuangwei, Wang, Yue, Ren, Yongfei, Pu, Xi, Liu, Na, Li, Rongkun, Wang, Xu, Dai, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307849/
https://www.ncbi.nlm.nih.gov/pubmed/35869042
http://dx.doi.org/10.1038/s41420-022-01127-w