The protective effect of DNA aptamer on osteonecrosis of the femoral head by alleviating TNF-α-mediated necroptosis via RIP1/RIP3/MLKL pathway

BACKGROUND: The process of necroptosis mediated by tumor necrosis factor alpha (TNF-α) might play an important role in the onset and development of the osteonecrosis of the femoral head (ONFH). The dysfunctions of bone microvascular endothelial cells (BMECs) have been identified as an important part...

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Detalles Bibliográficos
Autores principales: Fan, Xiaoyu, Xu, Xin, Wu, Xinjie, Xia, Runzhi, Gao, Fuqiang, Zhang, Qingyu, Sun, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307900/
https://www.ncbi.nlm.nih.gov/pubmed/35919280
http://dx.doi.org/10.1016/j.jot.2022.07.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307900/
https://www.ncbi.nlm.nih.gov/pubmed/35919280
http://dx.doi.org/10.1016/j.jot.2022.07.001

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