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HIV-1 Tat and cocaine impact astrocytic energy reservoirs and epigenetic regulation by influencing the LINC01133-hsa-miR-4726-5p-NDUFA9 axis

Clinical research has proven that HIV-positive (HIV(+)) individuals with cocaine abuse show behavioral and neurocognitive disorders. Noncoding RNAs (ncRNAs), such as long ncRNAs (lncRNAs) and microRNAs (miRNAs), are known to regulate gene expression in the contexts of HIV infection and drug abuse. H...

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Detalles Bibliográficos
Autores principales: Doke, Mayur, McLaughlin, Jay P., Cai, James J., Pendyala, Gurudutt, Kashanchi, Fatah, Khan, Mansoor A., Samikkannu, Thangavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307901/
https://www.ncbi.nlm.nih.gov/pubmed/35892093
http://dx.doi.org/10.1016/j.omtn.2022.07.001