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Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development

BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) is a multistep process whereby abnormally proliferating cancer cells undergo extensive metabolic reprogramming. Metabolic alterations in hepatocarcinogenesis depend on the activation of specific oncogenes, thus partially explaining HCC heterogeneit...

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Detalles Bibliográficos
Autores principales:	Serra, Marina, Di Matteo, Mario, Serneels, Jens, Pal, Rajesh, Cafarello, Sarah Trusso, Lanza, Martina, Sanchez-Martin, Carlos, Evert, Matthias, Castegna, Alessandra, Calvisi, Diego Francesco, Mazzone, Massimiliano, Columbano, Amedeo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307943/ https://www.ncbi.nlm.nih.gov/pubmed/35714859 http://dx.doi.org/10.1016/j.jcmgh.2022.06.003

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