A peptoid-based inhibitor of protein arginine methyltransferase 1 (PRMT1) induces apoptosis and autophagy in cancer cells

Protein arginine methyltransferases (PRMTs) are S-adenosylmethionine-dependent enzymes that transfer a methyl group to arginine residues within proteins, most notably histones. The nine characterized PRMT family members are divided into three types depending on the resulting methylated product: asym...

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Detalles Bibliográficos
Autores principales: Brekker, Mollie A., Sartawi, Tala, Sawatzky, Tina M., Causey, Corey P., Rehman, Fatima Khwaja, Knuckley, Bryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307946/
https://www.ncbi.nlm.nih.gov/pubmed/35764172
http://dx.doi.org/10.1016/j.jbc.2022.102205

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