Cargando…

Imidazole Derivative As a Novel Translation Inhibitor

Searching for novel compounds with antibiotic activity and understanding their mechanism of action is extremely important. The ribosome is one of the main targets for antibiotics in bacterial cells. Even if the molecule does not suit the clinical application for whatever reasons, an investigation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lukianov, D. A., Buev, V. S., Ivanenkov, Y. A., Kartsev, V. G., Skvortsov, D. A., Osterman, I. A., Sergiev, P. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	A.I. Gordeyev 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307981/ https://www.ncbi.nlm.nih.gov/pubmed/35923569 http://dx.doi.org/10.32607/actanaturae.11654

Ejemplares similares

Techniques for Screening Translation Inhibitors
por: Osterman, Ilya A., et al.
Publicado: (2016)

From Toxicity to Selectivity: Coculture of the Fluorescent Tumor and Non-Tumor Lung Cells and High-Throughput Screening of Anticancer Compounds
por: Skvortsov, D.A., et al.
Publicado: (2021)

Quality Control Mechanisms in Bacterial Translation
por: Zarechenskaia, A. S., et al.
Publicado: (2021)

Identification of Novel Antibacterials Using Machine Learning Techniques
por: Ivanenkov, Yan A., et al.
Publicado: (2019)

Comparison of mRNA features affecting translation initiation and reinitiation
por: Osterman, Ilya A., et al.
Publicado: (2013)

Bioprospecting for the soil-derived actinobacteria and bioactive secondary metabolites on the Western Qinghai-Tibet Plateau
por: Liu, Lifang, et al.
Publicado: (2023)

Bioprospecting of Soil-Derived Actinobacteria Along the Alar-Hotan Desert Highway in the Taklamakan Desert
por: Liu, Shaowei, et al.
Publicado: (2021)

Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state
por: Osterman, Ilya A., et al.
Publicado: (2017)

Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome
por: Prokhorova, Irina V., et al.
Publicado: (2016)

Flow-Seq Method: Features and Application in Bacterial Translation Studies
por: Komarova, E. S., et al.
Publicado: (2022)

Multifaceted Mechanism of Amicoumacin A Inhibition of Bacterial Translation
por: Maksimova, Elena M., et al.
Publicado: (2021)

Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin
por: Paranjpe, Madhura N, et al.
Publicado: (2022)

Translation at first sight: the influence of leading codons
por: Osterman, Ilya A, et al.
Publicado: (2020)

Flow-Seq Evaluation of Translation Driven by a Set of Natural Escherichia coli 5′-UTR of Variable Length
por: Komarova, Ekaterina S., et al.
Publicado: (2022)

Mechanism of translation inhibition by type II GNAT toxin AtaT2
por: Ovchinnikov, Stepan V, et al.
Publicado: (2020)

Survival guide: Escherichia coli in the stationary phase
por: Pletnev, P., et al.
Publicado: (2015)

Conjugates of Chloramphenicol Amine and Berberine as Antimicrobial Agents
por: Pavlova, Julia A., et al.
Publicado: (2022)

Mechanism-Based Approach to New Antibiotic Producers Screening among Actinomycetes in the Course of the Citizen Science Project
por: Volynkina, Inna A., et al.
Publicado: (2022)

How much can we learn about the function of bacterial rRNA modification by mining large-scale experimental datasets?
por: Sergiev, Petr V., et al.
Publicado: (2012)

Influence of the spacer region between the Shine–Dalgarno box and the start codon for fine‐tuning of the translation efficiency in Escherichia coli
por: Komarova, Ekaterina S., et al.
Publicado: (2020)

Design and Antioxidant Properties of Bifunctional 2H-Imidazole-Derived Phenolic Compounds—A New Family of Effective Inhibitors for Oxidative Stress-Associated Destructive Processes
por: Gerasimova, Elena L., et al.
Publicado: (2021)

Hetiamacin E and F, New Amicoumacin Antibiotics from Bacillus subtilis PJS Using MS/MS-Based Molecular Networking
por: Wang, Ting, et al.
Publicado: (2020)

Synthesis and Biological Evaluation of Novel Dispiro-Indolinones with Anticancer Activity
por: Ivanenkov, Yan A., et al.
Publicado: (2023)

Transcranial cerebral oximetry (TCCO) monitoring in neurosurgical critically ill patients
por: Toma, G, et al.
Publicado: (2003)

Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds
por: Niculescu-Duvaz, Dan, et al.
Publicado: (2010)

A New Albomycin-Producing Strain of Streptomyces globisporus subsp. globisporus May Provide Protection for Ants Messor structor
por: Zakalyukina, Yuliya V., et al.
Publicado: (2022)

In-silico and in-vitro functional validation of imidazole derivatives as potential sirtuin inhibitor
por: Dindi, Uma Maheswara Rao, et al.
Publicado: (2023)

Imidazole and Imidazolium Antibacterial Drugs Derived from Amino Acids
por: Valls, Adriana, et al.
Publicado: (2020)

Novel Group of Imidazole Derivatives as Atypical Selective Cyclooxygenase-2 Inhibitors: Design, Synthesis and Biological Evaluation
por: Kiani, Azin, et al.
Publicado: (2018)

RtcB2-PrfH Operon Protects E. coli ATCC25922 Strain from Colicin E3 Toxin
por: Maviza, Tinashe P., et al.
Publicado: (2022)

1-(4-Phenoxybenzyl) 5-Aminouracil Derivatives and Their Analogues – Novel Inhibitors of Human Adenovirus Replication
por: Nikitenko, N. A., et al.
Publicado: (2018)

Synthesis and in vitro study of novel borneol derivatives as potent inhibitors of the influenza A virus
por: Sokolova, A. S., et al.
Publicado: (2017)

Application of sorting and next generation sequencing to study 5΄-UTR influence on translation efficiency in Escherichia coli
por: Evfratov, Sergey A., et al.
Publicado: (2017)

Triphenilphosphonium Analogs of Chloramphenicol as Dual-Acting Antimicrobial and Antiproliferating Agents
por: Pavlova, Julia A., et al.
Publicado: (2021)

Three thousand years of magnets
por: Kartsev, V P
Publicado: (1975)

Sensitizing tumor cells to conventional drugs: HSP70 chaperone inhibitors, their selection and application in cancer models
por: Lazarev, Vladimir F., et al.
Publicado: (2018)

A novel viewpoint of an imidazole derivative ionic liquid as an additive for cobalt and nickel electrodeposition
por: Omar, Inam M. A., et al.
Publicado: (2020)

Quinoline–imidazole/benzimidazole derivatives as dual-/multi-targeting hybrids inhibitors with anticancer and antimicrobial activity
por: Diaconu, Dumitrela, et al.
Publicado: (2022)

Chemoinformatics Studies on a Series of Imidazoles as Cruzain Inhibitors
por: Medeiros, Alex R., et al.
Publicado: (2021)

Synthesis and Evaluation of N-substituted Imidazole Derivatives for Antimicrobial Activity
por: Gupta, Namita, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_jvpkngsfucqrqbe78a7cti1k30