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Spectral fiber photometry derives hemoglobin concentration changes for accurate measurement of fluorescent sensor activity

Fiber photometry is an emerging technique for recording fluorescent sensor activity in the brain. However, significant hemoglobin absorption artifacts in fiber photometry data may be misinterpreted as sensor activity changes. Because hemoglobin exists widely in the brain, and its concentration varie...

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Detalles Bibliográficos
Autores principales: Zhang, Wei-Ting, Chao, Tzu-Hao Harry, Yang, Yue, Wang, Tzu-Wen, Lee, Sung-Ho, Oyarzabal, Esteban A., Zhou, Jingheng, Nonneman, Randy, Pegard, Nicolas C., Zhu, Hongtu, Cui, Guohong, Shih, Yen-Yu Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308135/
https://www.ncbi.nlm.nih.gov/pubmed/35880016
http://dx.doi.org/10.1016/j.crmeth.2022.100243