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Exosomes from mmu_circ_0001052-modified adipose-derived stem cells promote angiogenesis of DFU via miR-106a-5p and FGF4/p38MAPK pathway

BACKGROUND: Diabetic foot ulcer (DFU) is a chronic infectious disease caused by diabetes mellitus (DM). Angiogenesis plays the decisive role in wound healing of DFU. Adipose-derived stem cells (ADSCs) can ameliorate angiogenesis in DFU by exosomes. This study aims to determine the mechanism of exoso...

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Detalles Bibliográficos
Autores principales: Liang, Zun-Hong, Pan, Nan-Fang, Lin, Shi-Shuai, Qiu, Zhi-Yang, Liang, Ping, Wang, Jun, Zhang, Zhi, Pan, Yun-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308214/
https://www.ncbi.nlm.nih.gov/pubmed/35870977
http://dx.doi.org/10.1186/s13287-022-03015-7