FBXL17/spastin axis as a novel therapeutic target of hereditary spastic paraplegia

BACKGROUND: Spastin significantly influences microtubule regulation in neurons and is implicated in the pathogenesis of hereditary spastic paraplegia (HSP). However, post-translational regulation of the spastin protein remains nebulous. The association between E3 ubiquitin ligase and spastin provide...

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Detalles Bibliográficos
Autores principales: Kang, Hyun Mi, Kim, Dae Hun, Kim, Mijin, Min, Yoohong, Jeong, Bohyeon, Noh, Kyung Hee, Lee, Da Yong, Cho, Hyun-Soo, Kim, Nam-Soon, Jung, Cho-Rok, Lim, Jung Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308218/
https://www.ncbi.nlm.nih.gov/pubmed/35869491
http://dx.doi.org/10.1186/s13578-022-00851-1

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