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IFN-γ enhances the efficacy of mesenchymal stromal cell-derived exosomes via miR-21 in myocardial infarction rats

BACKGROUND: Mesenchymal stromal cells (MSCs) activated with IFN-γ elicit stronger physical effects. Exosomes (Exos) secreted from MSCs show protective effects against myocardial injury. This study aimed to determine whether Exos derived from IFN-γ-treated MSCs exhibit more potent cardioprotective fu...

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Detalles Bibliográficos
Autores principales:	Zhang, Jian, Lu, Yao, Mao, Yangming, Yu, Yue, Wu, Tianyu, Zhao, Wei, Zhu, Yeqian, Zhao, Pengcheng, Zhang, Fengxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308256/ https://www.ncbi.nlm.nih.gov/pubmed/35870960 http://dx.doi.org/10.1186/s13287-022-02984-z

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