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ARHGEF37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating Cdc42

BACKGROUND: The extravasation capability of hepatocellular carcinoma (HCC) cells plays a vital role in distant metastasis. However, the underlying mechanism of extravasation in HCC lung metastasis remains largely unclear. METHODS: The expression of ARHGEF37 in human HCC specimens and HCC cell lines...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Ren, Liangliang, Wu, Junhua, Feng, Rongni, Chen, Yunyang, Li, Ronggang, Wu, Meimei, Zheng, Mingzhu, Wu, Xing Gui, Luo, Wanjun, He, Hongle, Huang, Yanming, Tang, Miaoling, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308268/
https://www.ncbi.nlm.nih.gov/pubmed/35869555
http://dx.doi.org/10.1186/s13046-022-02441-y

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