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SENP6 induces microglial polarization and neuroinflammation through de-SUMOylation of Annexin-A1 after cerebral ischaemia–reperfusion injury

BACKGROUND: Previous data have reported that Sentrin/SUMO-specific protease 6 (SENP6) is involved in ischaemic brain injury and induces neuronal apoptosis after cerebral ischaemia, but the role of SENP6 in microglia-induced neuroinflammation and its underlying mechanism remain poorly understood. Thi...

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Detalles Bibliográficos
Autores principales:	Mao, Meng, Xia, Qian, Zhan, Gao-Feng, Chu, Qin-Jun, Li, Xing, Lian, Hong-Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308285/ https://www.ncbi.nlm.nih.gov/pubmed/35869493 http://dx.doi.org/10.1186/s13578-022-00850-2

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