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Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling

BACKGROUND: Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have emerged as a powerful tool for disease modeling, though their immature nature currently limits translation into clinical practice. Maturation strategies increasingly pay attention to cardiac metabolism because of its pi...

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Detalles Bibliográficos
Autores principales: Vučković, Sofija, Dinani, Rafeeh, Nollet, Edgar E., Kuster, Diederik W. D., Buikema, Jan Willem, Houtkooper, Riekelt H., Nabben, Miranda, van der Velden, Jolanda, Goversen, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308297/
https://www.ncbi.nlm.nih.gov/pubmed/35870954
http://dx.doi.org/10.1186/s13287-022-03021-9