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A mirror-image analysis of psychiatric hospitalisations among people with severe mental illness using Independent Supported Housing

BACKGROUND: Evidence on the effectiveness of Independent Supported Housing (ISH) for non-homeless people with severe mental illness primarily comes from observational cohort studies, which have high risk of bias due to confounding by time-invariant sample characteristics. The present study proposes...

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Autores principales: Adamus, Christine, Zürcher, Simeon Joel, Richter, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308357/
https://www.ncbi.nlm.nih.gov/pubmed/35869456
http://dx.doi.org/10.1186/s12888-022-04133-5
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author Adamus, Christine
Zürcher, Simeon Joel
Richter, Dirk
author_facet Adamus, Christine
Zürcher, Simeon Joel
Richter, Dirk
author_sort Adamus, Christine
collection PubMed
description BACKGROUND: Evidence on the effectiveness of Independent Supported Housing (ISH) for non-homeless people with severe mental illness primarily comes from observational cohort studies, which have high risk of bias due to confounding by time-invariant sample characteristics. The present study proposes an alternative study design known from pharmacology to overcome this bias and strengthen evidence. METHODS: We conducted a retrospective mirror-image analysis with medical records of 144 ISH service users to assess the effectiveness of ISH in reducing the number and duration of hospitalisations. Outcomes occurring in equal periods before and during ISH utilisation were compared for every ISH user. Differences between the periods were tested with incidence rate ratios (IRR). RESULTS: Included service users were on average 38.2 years old, female (54%) and predominately had an affective (28.5%) or a schizophrenic or psychotic (22.9%) disorder with ISH utilisation days ranging from 36–960. Fewer admissions (IRR = 0.41, 95%-CI 0.27–0.64) and fewer person-days hospitalised (IRR = 0.38, 95%-CI 0.35–0.41) were observed during ISH utilisation compared to prior to their ISH utilisation. While the reduction in psychiatric admissions may be somewhat confounded by time-variant characteristics, the substantial reduction in hospitalised bed-bays represents at least partially an intervention effect. CONCLUSIONS: The mirror-image study design allowed for a cost-effective investigation of ISH effectiveness in reducing hospitalisation without confounding by time-invariant sample characteristics. We provide recommendations for the design’s application and suggest further research with larger samples.
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spelling pubmed-93083572022-07-24 A mirror-image analysis of psychiatric hospitalisations among people with severe mental illness using Independent Supported Housing Adamus, Christine Zürcher, Simeon Joel Richter, Dirk BMC Psychiatry Research Article BACKGROUND: Evidence on the effectiveness of Independent Supported Housing (ISH) for non-homeless people with severe mental illness primarily comes from observational cohort studies, which have high risk of bias due to confounding by time-invariant sample characteristics. The present study proposes an alternative study design known from pharmacology to overcome this bias and strengthen evidence. METHODS: We conducted a retrospective mirror-image analysis with medical records of 144 ISH service users to assess the effectiveness of ISH in reducing the number and duration of hospitalisations. Outcomes occurring in equal periods before and during ISH utilisation were compared for every ISH user. Differences between the periods were tested with incidence rate ratios (IRR). RESULTS: Included service users were on average 38.2 years old, female (54%) and predominately had an affective (28.5%) or a schizophrenic or psychotic (22.9%) disorder with ISH utilisation days ranging from 36–960. Fewer admissions (IRR = 0.41, 95%-CI 0.27–0.64) and fewer person-days hospitalised (IRR = 0.38, 95%-CI 0.35–0.41) were observed during ISH utilisation compared to prior to their ISH utilisation. While the reduction in psychiatric admissions may be somewhat confounded by time-variant characteristics, the substantial reduction in hospitalised bed-bays represents at least partially an intervention effect. CONCLUSIONS: The mirror-image study design allowed for a cost-effective investigation of ISH effectiveness in reducing hospitalisation without confounding by time-invariant sample characteristics. We provide recommendations for the design’s application and suggest further research with larger samples. BioMed Central 2022-07-22 /pmc/articles/PMC9308357/ /pubmed/35869456 http://dx.doi.org/10.1186/s12888-022-04133-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Adamus, Christine
Zürcher, Simeon Joel
Richter, Dirk
A mirror-image analysis of psychiatric hospitalisations among people with severe mental illness using Independent Supported Housing
title A mirror-image analysis of psychiatric hospitalisations among people with severe mental illness using Independent Supported Housing
title_full A mirror-image analysis of psychiatric hospitalisations among people with severe mental illness using Independent Supported Housing
title_fullStr A mirror-image analysis of psychiatric hospitalisations among people with severe mental illness using Independent Supported Housing
title_full_unstemmed A mirror-image analysis of psychiatric hospitalisations among people with severe mental illness using Independent Supported Housing
title_short A mirror-image analysis of psychiatric hospitalisations among people with severe mental illness using Independent Supported Housing
title_sort mirror-image analysis of psychiatric hospitalisations among people with severe mental illness using independent supported housing
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308357/
https://www.ncbi.nlm.nih.gov/pubmed/35869456
http://dx.doi.org/10.1186/s12888-022-04133-5
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