Knockdown of myorg leads to brain calcification in zebrafish

Primary familial brain calcification (PFBC) is a neurogenetic disorder characterized by bilateral calcified deposits in the brain. We previously identified that MYORG as the first pathogenic gene for autosomal recessive PFBC, and established a Myorg-KO mouse model. However, Myorg-KO mice developed b...

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Detalles Bibliográficos
Autores principales: Zhao, Miao, Lin, Xiao-Hong, Zeng, Yi-Heng, Su, Hui-Zhen, Wang, Chong, Yang, Kang, Chen, Yi-Kun, Lin, Bi-Wei, Yao, Xiang-Ping, Chen, Wan-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308368/
https://www.ncbi.nlm.nih.gov/pubmed/35870928
http://dx.doi.org/10.1186/s13041-022-00953-4

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