Pure Androgen-Secreting Radiologically Suspicious Adrenal Mass: Benign or Malignant?

Pure androgen-secreting adrenocortical tumors (PASATs) are rare entities. Their clinical presentations include virilizing features that vary based on age and gender. The pathogenesis of this tumor is still unclear, with around 50% of such tumors being malignant. Imaging characteristics of the tumor...

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Autores principales: Gopinath, Chaitra, Shekar, Suman, Acharya, Madan, Pattan, Vishwanath, Sundaresh, Vishnu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Endocrinology/Diabetes/Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308385/
https://www.ncbi.nlm.nih.gov/pubmed/35898370
http://dx.doi.org/10.7759/cureus.26234
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author Gopinath, Chaitra
Shekar, Suman
Acharya, Madan
Pattan, Vishwanath
Sundaresh, Vishnu
author_facet Gopinath, Chaitra
Shekar, Suman
Acharya, Madan
Pattan, Vishwanath
Sundaresh, Vishnu
author_sort Gopinath, Chaitra
collection PubMed
description Pure androgen-secreting adrenocortical tumors (PASATs) are rare entities. Their clinical presentations include virilizing features that vary based on age and gender. The pathogenesis of this tumor is still unclear, with around 50% of such tumors being malignant. Imaging characteristics of the tumor on CT/MRI including size, heterogenicity, and contrast wash-out time are used to predict malignancy. Surgical excision is recommended for all functional adrenal tumors. In this report, we discuss a case of a 68-year-old postmenopausal female presenting with hyperandrogenism and was found to have a 7-cm, PASAT that raised suspicion for malignancy on CT scan, but was determined to be benign on surgical pathology.
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spelling pubmed-93083852022-07-26 Pure Androgen-Secreting Radiologically Suspicious Adrenal Mass: Benign or Malignant? Gopinath, Chaitra Shekar, Suman Acharya, Madan Pattan, Vishwanath Sundaresh, Vishnu Cureus Endocrinology/Diabetes/Metabolism Pure androgen-secreting adrenocortical tumors (PASATs) are rare entities. Their clinical presentations include virilizing features that vary based on age and gender. The pathogenesis of this tumor is still unclear, with around 50% of such tumors being malignant. Imaging characteristics of the tumor on CT/MRI including size, heterogenicity, and contrast wash-out time are used to predict malignancy. Surgical excision is recommended for all functional adrenal tumors. In this report, we discuss a case of a 68-year-old postmenopausal female presenting with hyperandrogenism and was found to have a 7-cm, PASAT that raised suspicion for malignancy on CT scan, but was determined to be benign on surgical pathology. Cureus 2022-06-23 /pmc/articles/PMC9308385/ /pubmed/35898370 http://dx.doi.org/10.7759/cureus.26234 Text en Copyright © 2022, Gopinath et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Gopinath, Chaitra
Shekar, Suman
Acharya, Madan
Pattan, Vishwanath
Sundaresh, Vishnu
Pure Androgen-Secreting Radiologically Suspicious Adrenal Mass: Benign or Malignant?
title Pure Androgen-Secreting Radiologically Suspicious Adrenal Mass: Benign or Malignant?
title_full Pure Androgen-Secreting Radiologically Suspicious Adrenal Mass: Benign or Malignant?
title_fullStr Pure Androgen-Secreting Radiologically Suspicious Adrenal Mass: Benign or Malignant?
title_full_unstemmed Pure Androgen-Secreting Radiologically Suspicious Adrenal Mass: Benign or Malignant?
title_short Pure Androgen-Secreting Radiologically Suspicious Adrenal Mass: Benign or Malignant?
title_sort pure androgen-secreting radiologically suspicious adrenal mass: benign or malignant?
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308385/
https://www.ncbi.nlm.nih.gov/pubmed/35898370
http://dx.doi.org/10.7759/cureus.26234
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