Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome

GATA2 mutation can result in profoundly reduced monocytes, dendritic cells, natural killer cells, and B cells, and is associated with a predisposition for recurrent and disseminated nontuberculous mycobacterial (NTM) infections and myelodysplasias. Herein, we describe a unique case of 3 simultaneous...

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Autores principales: Tabaja, Hussam, Jensen, Kelsey L, Rivera, Christina G, Misra, Anisha, Pruthi, Rajiv K, Vergidis, Paschalis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308453/
https://www.ncbi.nlm.nih.gov/pubmed/35891688
http://dx.doi.org/10.1093/ofid/ofac309
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author Tabaja, Hussam
Jensen, Kelsey L
Rivera, Christina G
Misra, Anisha
Pruthi, Rajiv K
Vergidis, Paschalis
author_facet Tabaja, Hussam
Jensen, Kelsey L
Rivera, Christina G
Misra, Anisha
Pruthi, Rajiv K
Vergidis, Paschalis
author_sort Tabaja, Hussam
collection PubMed
description GATA2 mutation can result in profoundly reduced monocytes, dendritic cells, natural killer cells, and B cells, and is associated with a predisposition for recurrent and disseminated nontuberculous mycobacterial (NTM) infections and myelodysplasias. Herein, we describe a unique case of 3 simultaneous disseminated NTM infections in a patient with GATA2 mutations.
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spelling pubmed-93084532022-07-25 Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome Tabaja, Hussam Jensen, Kelsey L Rivera, Christina G Misra, Anisha Pruthi, Rajiv K Vergidis, Paschalis Open Forum Infect Dis Brief Report GATA2 mutation can result in profoundly reduced monocytes, dendritic cells, natural killer cells, and B cells, and is associated with a predisposition for recurrent and disseminated nontuberculous mycobacterial (NTM) infections and myelodysplasias. Herein, we describe a unique case of 3 simultaneous disseminated NTM infections in a patient with GATA2 mutations. Oxford University Press 2022-06-28 /pmc/articles/PMC9308453/ /pubmed/35891688 http://dx.doi.org/10.1093/ofid/ofac309 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Tabaja, Hussam
Jensen, Kelsey L
Rivera, Christina G
Misra, Anisha
Pruthi, Rajiv K
Vergidis, Paschalis
Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome
title Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome
title_full Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome
title_fullStr Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome
title_full_unstemmed Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome
title_short Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome
title_sort multiple simultaneous infections with nontuberculous mycobacteria in the setting of gata2 mutation and myelodysplastic syndrome
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308453/
https://www.ncbi.nlm.nih.gov/pubmed/35891688
http://dx.doi.org/10.1093/ofid/ofac309
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