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Treatment of Down Syndrome-Associated Arthritis with JAK Inhibition
Down syndrome (DS) results from a trisomy of chromosome 21, which causes immune dysregulation that leads to hyperactivation of interferon and Janus kinase (JAK) signaling. This results in complex medical abnormalities in the immune system and an increase in autoimmune and autoinflammatory conditions...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308516/ https://www.ncbi.nlm.nih.gov/pubmed/35879952 http://dx.doi.org/10.1155/2022/4889102 |