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Cortical abnormalities of synaptic vesicle protein 2A in focal cortical dysplasia type II identified in vivo with (18)F-SynVesT-1 positron emission tomography imaging

PURPOSE: The loss of synaptic vesicle glycoprotein 2A (SV2A) is well established as the major correlate of epileptogenesis in focal cortical dysplasia type II (FCD II), but this has not been directly tested in vivo. In this positron emission tomography (PET) study with the new tracer (18)F-SynVesT-1...

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Detalles Bibliográficos
Autores principales: Tang, Yongxiang, Yu, Jie, Zhou, Ming, Li, Jian, Long, Tingting, Li, Yulai, Feng, Li, Chen, Dengming, Yang, Zhiquan, Huang, Yiyun, Hu, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308579/
https://www.ncbi.nlm.nih.gov/pubmed/34978594
http://dx.doi.org/10.1007/s00259-021-05665-w