Elevated Urinary Rab10 Phosphorylation in Idiopathic Parkinson Disease

BACKGROUND: Pathogenic leucine‐rich repeat kinase 2 LRRK2 mutations may increase LRRK2 kinase activity and Rab substrate phosphorylation. Genetic association studies link variation in LRRK2 to idiopathic Parkinson disease (iPD) risk. OBJECTIVES: Through measurements of the LRRK2 kinase substrate pT7...

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Detalles Bibliográficos
Autores principales: Wang, Shijie, Unnithan, Shakthi, Bryant, Nicole, Chang, Allison, Rosenthal, Liana S., Pantelyat, Alexander, Dawson, Ted M., Al‐Khalidi, Hussein R., West, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Regular Issue Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308673/
https://www.ncbi.nlm.nih.gov/pubmed/35521944
http://dx.doi.org/10.1002/mds.29043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308673/
https://www.ncbi.nlm.nih.gov/pubmed/35521944
http://dx.doi.org/10.1002/mds.29043

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