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Context‐Dependence of the Reactivity of Cysteine and Lysine Residues
The S‐alkylation of Cys residues with a maleimide and the N (ϵ)‐acylation of Lys residues with an N‐hydroxysuccinimide (NHS) ester are common methods for bioconjugation. Using Cys and Lys derivatives as proxies, we assessed differences in reactivity depending on the position of Cys or Lys in a prote...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308718/ https://www.ncbi.nlm.nih.gov/pubmed/35527228 http://dx.doi.org/10.1002/cbic.202200258 |