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Extensive co-binding and rapid redistribution of NANOG and GATA6 during emergence of divergent lineages

Fate-determining transcription factors (TFs) can promote lineage-restricted transcriptional programs from common progenitor states. The inner cell mass (ICM) of mouse blastocysts co-expresses the TFs NANOG and GATA6, which drive the bifurcation of the ICM into either the epiblast (Epi) or the primit...

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Detalles Bibliográficos
Autores principales:	Thompson, Joyce J., Lee, Daniel J., Mitra, Apratim, Frail, Sarah, Dale, Ryan K., Rocha, Pedro P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308780/ https://www.ncbi.nlm.nih.gov/pubmed/35871075 http://dx.doi.org/10.1038/s41467-022-31938-5

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