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Antiviral activity of ouabain against a Brazilian Zika virus strain

Zika virus (ZIKV) is an emerging arbovirus associated with neurological disorders. Currently, no specific vaccines or antivirals are available to treat the ZIKV infection. Ouabain, a cardiotonic steroid known as Na(+)/K(+)-ATPase inhibitor, has been previously described as an immunomodulatory substa...

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Detalles Bibliográficos
Autores principales: Carvalho, Deyse Cristina Madruga, da Silva, Poliana Gomes, Dantas, Willyenne Marília, da Silva, Severino Jefferson Ribeiro, da Silva, Caroline Targino Alves, Chaves, Elton José Ferreira, de Araújo, Demetrius Antônio Machado, de Oliveira, Ronaldo Nascimento, Rodrigues-Mascarenhas, Sandra, Pena, Lindomar José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308787/
https://www.ncbi.nlm.nih.gov/pubmed/35871157
http://dx.doi.org/10.1038/s41598-022-14243-5