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Brain fractalkine-CX3CR1 signalling is anti-obesity system as anorexigenic and anti-inflammatory actions in diet-induced obese mice

Fractalkine is one of the CX3C chemokine family, and it is widely expressed in the brain including the hypothalamus. In the brain, fractalkine is expressed in neurons and binds to a CX3C chemokine receptor 1 (CX3CR1) in microglia. The hypothalamus regulates energy homeostasis of which dysregulation...

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Detalles Bibliográficos
Autores principales: Kawamura, Namiko, Katsuura, Goro, Yamada-Goto, Nobuko, Nakama, Riho, Kambe, Yuki, Miyata, Atsuro, Furuyashiki, Tomoyuki, Narumiya, Shuh, Ogawa, Yoshihiro, Inui, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308795/
https://www.ncbi.nlm.nih.gov/pubmed/35871167
http://dx.doi.org/10.1038/s41598-022-16944-3

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