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Prevalence and associated factors of osteoarthritis in the Ural Eye and Medical Study and the Ural Very Old Study

To determine the prevalence of osteoarthritis and its associated factors in populations from Russia. The population-based Ural Eye and Medical Study (UEMS) and the population-based Ural Very Old Study (UVOS) were conducted in a rural and urban region in Bashkortostan/Russia and included participants...

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Autores principales: Bikbov, Mukharram M., Kazakbaeva, Gyulli M., Gilmanshin, Timur R., Zainullin, Rinat M., Rakhimova, Ellina M., Fakhretdinova, Albina A., Tuliakova, Azaliia M., Rusakova, Iuliia A., Panda-Jonas, Songhomitra, Nuriev, Ildar F., Zaynetdinov, Artur F., Zinnatullin, Ainur A., Arslangareeva, Inga I., Gizzatov, Ainur V., Bolshakova, Natalia I., Safiullina, Kamilia R., Jonas, Jost B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308808/
https://www.ncbi.nlm.nih.gov/pubmed/35871091
http://dx.doi.org/10.1038/s41598-022-16925-6
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author Bikbov, Mukharram M.
Kazakbaeva, Gyulli M.
Gilmanshin, Timur R.
Zainullin, Rinat M.
Rakhimova, Ellina M.
Fakhretdinova, Albina A.
Tuliakova, Azaliia M.
Rusakova, Iuliia A.
Panda-Jonas, Songhomitra
Nuriev, Ildar F.
Zaynetdinov, Artur F.
Zinnatullin, Ainur A.
Arslangareeva, Inga I.
Gizzatov, Ainur V.
Bolshakova, Natalia I.
Safiullina, Kamilia R.
Jonas, Jost B.
author_facet Bikbov, Mukharram M.
Kazakbaeva, Gyulli M.
Gilmanshin, Timur R.
Zainullin, Rinat M.
Rakhimova, Ellina M.
Fakhretdinova, Albina A.
Tuliakova, Azaliia M.
Rusakova, Iuliia A.
Panda-Jonas, Songhomitra
Nuriev, Ildar F.
Zaynetdinov, Artur F.
Zinnatullin, Ainur A.
Arslangareeva, Inga I.
Gizzatov, Ainur V.
Bolshakova, Natalia I.
Safiullina, Kamilia R.
Jonas, Jost B.
author_sort Bikbov, Mukharram M.
collection PubMed
description To determine the prevalence of osteoarthritis and its associated factors in populations from Russia. The population-based Ural Eye and Medical Study (UEMS) and the population-based Ural Very Old Study (UVOS) were conducted in a rural and urban region in Bashkortostan/Russia and included participants aged 40+ and 85+ years, respectively. As part of a detailed systematic examination, we assessed the osteoarthritis prevalence in an interview including questions on the self-reported presence of osteoarthritis, the joints affected and osteoarthritis-related pain-relieving therapy taken. Out of 5898 participants of the UEMS, 1636 individuals had osteoarthritis [prevalence: 27.7%; 95% confidence interval (CI) 26.7, 28.7], with 816 individuals (13.8%; 95% CI 12.8, 14.8) taking pain-relieving medication. A higher osteoarthritis prevalence was associated (multivariable analysis) with older age [odds ratio (OR 1.04; 95% confidence interval (CI) 1.03, 1.05], urban region of residence (OR 1.25; 95% CI 1.07, 1.45), higher body mass index (BMI) (OR 1.04; 95% CI 1.03, 1.06), lower monthly income (OR 0.78; 95% CI 0.68, 0.90), higher physical activity score (OR 1.02, 95% CI 1.01, 1.03), higher prevalence of a history of cardiovascular disease including stroke (OR 1.55; 95% CI 1.33, 1.81), previous bone fractures (OR 1.20; 95% CI 1.04, 1.40) and previous falls (OR 1.22; 95% CI 1.03, 1.45), higher hearing loss score (OR 1.01; 95% CI 1.01, 1.02), and less alcohol consumption (OR 0.78; 95% CI 0.65, 0.93). Out of 1526 UVOS participants, 567 individuals had osteoarthritis (prevalence: 37.2%; 95% CI 35.0, 40.0), with 195 (12.8%; 95% CI 11.3, 14.3) individuals taking pain-relieving medication. Higher osteoarthritis prevalence was associated with rural region of habitation (OR 1.69; 95% CI 1.20, 2.38), lower monthly income (OR 0.62; 95% CI 0.46, 0.84), higher prevalence of cardiovascular disease (OR 1.75; 95% CI 1.30, 2.36), and higher anxiety score (OR 1.04; 95% CI 1.03, 1.06). Osteoarthritis and use of pain-relieving medication are common in these populations in Russia. Main associated factors were older age and lower monthly income in both study populations, female sex, higher BMI, urban region, and previous falls and bone fractures in the UEMS population, and rural region and a higher anxiety score in the UVOS study population.
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spelling pubmed-93088082022-07-25 Prevalence and associated factors of osteoarthritis in the Ural Eye and Medical Study and the Ural Very Old Study Bikbov, Mukharram M. Kazakbaeva, Gyulli M. Gilmanshin, Timur R. Zainullin, Rinat M. Rakhimova, Ellina M. Fakhretdinova, Albina A. Tuliakova, Azaliia M. Rusakova, Iuliia A. Panda-Jonas, Songhomitra Nuriev, Ildar F. Zaynetdinov, Artur F. Zinnatullin, Ainur A. Arslangareeva, Inga I. Gizzatov, Ainur V. Bolshakova, Natalia I. Safiullina, Kamilia R. Jonas, Jost B. Sci Rep Article To determine the prevalence of osteoarthritis and its associated factors in populations from Russia. The population-based Ural Eye and Medical Study (UEMS) and the population-based Ural Very Old Study (UVOS) were conducted in a rural and urban region in Bashkortostan/Russia and included participants aged 40+ and 85+ years, respectively. As part of a detailed systematic examination, we assessed the osteoarthritis prevalence in an interview including questions on the self-reported presence of osteoarthritis, the joints affected and osteoarthritis-related pain-relieving therapy taken. Out of 5898 participants of the UEMS, 1636 individuals had osteoarthritis [prevalence: 27.7%; 95% confidence interval (CI) 26.7, 28.7], with 816 individuals (13.8%; 95% CI 12.8, 14.8) taking pain-relieving medication. A higher osteoarthritis prevalence was associated (multivariable analysis) with older age [odds ratio (OR 1.04; 95% confidence interval (CI) 1.03, 1.05], urban region of residence (OR 1.25; 95% CI 1.07, 1.45), higher body mass index (BMI) (OR 1.04; 95% CI 1.03, 1.06), lower monthly income (OR 0.78; 95% CI 0.68, 0.90), higher physical activity score (OR 1.02, 95% CI 1.01, 1.03), higher prevalence of a history of cardiovascular disease including stroke (OR 1.55; 95% CI 1.33, 1.81), previous bone fractures (OR 1.20; 95% CI 1.04, 1.40) and previous falls (OR 1.22; 95% CI 1.03, 1.45), higher hearing loss score (OR 1.01; 95% CI 1.01, 1.02), and less alcohol consumption (OR 0.78; 95% CI 0.65, 0.93). Out of 1526 UVOS participants, 567 individuals had osteoarthritis (prevalence: 37.2%; 95% CI 35.0, 40.0), with 195 (12.8%; 95% CI 11.3, 14.3) individuals taking pain-relieving medication. Higher osteoarthritis prevalence was associated with rural region of habitation (OR 1.69; 95% CI 1.20, 2.38), lower monthly income (OR 0.62; 95% CI 0.46, 0.84), higher prevalence of cardiovascular disease (OR 1.75; 95% CI 1.30, 2.36), and higher anxiety score (OR 1.04; 95% CI 1.03, 1.06). Osteoarthritis and use of pain-relieving medication are common in these populations in Russia. Main associated factors were older age and lower monthly income in both study populations, female sex, higher BMI, urban region, and previous falls and bone fractures in the UEMS population, and rural region and a higher anxiety score in the UVOS study population. Nature Publishing Group UK 2022-07-23 /pmc/articles/PMC9308808/ /pubmed/35871091 http://dx.doi.org/10.1038/s41598-022-16925-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Bikbov, Mukharram M.
Kazakbaeva, Gyulli M.
Gilmanshin, Timur R.
Zainullin, Rinat M.
Rakhimova, Ellina M.
Fakhretdinova, Albina A.
Tuliakova, Azaliia M.
Rusakova, Iuliia A.
Panda-Jonas, Songhomitra
Nuriev, Ildar F.
Zaynetdinov, Artur F.
Zinnatullin, Ainur A.
Arslangareeva, Inga I.
Gizzatov, Ainur V.
Bolshakova, Natalia I.
Safiullina, Kamilia R.
Jonas, Jost B.
Prevalence and associated factors of osteoarthritis in the Ural Eye and Medical Study and the Ural Very Old Study
title Prevalence and associated factors of osteoarthritis in the Ural Eye and Medical Study and the Ural Very Old Study
title_full Prevalence and associated factors of osteoarthritis in the Ural Eye and Medical Study and the Ural Very Old Study
title_fullStr Prevalence and associated factors of osteoarthritis in the Ural Eye and Medical Study and the Ural Very Old Study
title_full_unstemmed Prevalence and associated factors of osteoarthritis in the Ural Eye and Medical Study and the Ural Very Old Study
title_short Prevalence and associated factors of osteoarthritis in the Ural Eye and Medical Study and the Ural Very Old Study
title_sort prevalence and associated factors of osteoarthritis in the ural eye and medical study and the ural very old study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308808/
https://www.ncbi.nlm.nih.gov/pubmed/35871091
http://dx.doi.org/10.1038/s41598-022-16925-6
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