Highly mutated monoclonal antibody 3F2 targets a conformational and strain-restricted epitope in human immunodeficiency virus gp41 with significant antibody-dependent cell cytotoxicity

Identifying epitope targets by studying the native antibody (Ab) response can identify potential novel vaccine constructs. Studies suggest that long-term non-progressor (LTNP) subjects have inherent immune mechanisms that help to control viremia and disease progression. To explore a role for antibod...

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Detalles Bibliográficos
Autores principales: DeCotes, Devin, Baron, Sarah, Hoffman, Jonathon, Garrett, Meghan, Sojar, Hakimuddin, Hicar, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308897/
https://www.ncbi.nlm.nih.gov/pubmed/35871426
http://dx.doi.org/10.1007/s00705-022-05518-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308897/
https://www.ncbi.nlm.nih.gov/pubmed/35871426
http://dx.doi.org/10.1007/s00705-022-05518-3

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